Xinchen supplies high-purity polar aprotic solvents for qualified global B2B buyers, including DMF, DMAC, DMSO, NMP and acetonitrile. CAS number, purity, water content, low metal requirements, SDS, COA, TDS, packaging and export feasibility should be confirmed before shipment.
High-Purity Solvents
Focused solvent options for synthesis, purification, pharmaceutical intermediates, electronics, polymers and material processing.
Specification Review
Confirm CAS number, assay, moisture, acidity, appearance, impurities, grade and current batch COA before ordering.
Export Support
SDS, COA, TDS, packaging details and dangerous goods transport checks can be coordinated by product and destination.
Polar Aprotic Solvent Product List
This list helps buyers compare CAS number, purity and typical application before requesting a quotation.
| Product | CAS No. | Purity | Typical Use | Category |
|---|---|---|---|---|
| Acetonitrile | 75-05-8 | ≥99.9% | Chromatography, extraction, purification, synthesis and electronic chemical use | Specialty Chemicals |
| Dimethyl Sulfoxide (DMSO) | 67-68-5 | ≥99.9% | Strong polar solvent for synthesis, purification and specialty chemical processing | Amides |
| N-Methyl-2-Pyrrolidone (NMP) | 872-50-4 | ≥99.5% | High-boiling solvent for electronics, polymers, coatings and material processing | Amides |
| N,N-Dimethylacetamide (DMAC) | 127-19-5 | ≥99.9% | Polar solvent for fibers, polymers, synthesis and pharmaceutical intermediates | Amides |
| N,N-Dimethylformamide (DMF) | 68-12-2 | ≥99.9% | Polar aprotic solvent for pharmaceuticals, synthesis, resins and purification | Amides |
Procurement Checks
Quality Items
- Assay, water content, acidity, color and appearance
- Low metal, low residue or application-specific grade requirements
- Current batch COA and storage condition confirmation
Documentation Items
- SDS, MSDS, COA, TDS and packaging details
- UN number, hazard class and packing group where applicable
- Destination country, port, quantity and packaging preference
Choosing Among High-Purity Polar Aprotic Solvents
DMF, DMAC, DMSO, NMP and acetonitrile differ in boiling range, viscosity, solvency, water miscibility, recovery behavior and regulatory profile. Selection should begin with process compatibility and separation requirements, then move to the impurity limits that affect yield, color, residue or downstream purification.
For a meaningful supplier comparison, use the same grade definition and analytical scope. Confirm assay, water, acidity, color and relevant individual impurities, along with packaging material, storage controls and current batch documentation. Process owners should evaluate substitution through qualified trials rather than assuming that solvents in the same broad family are interchangeable.
Frequently Asked Questions
Can polar aprotic solvents be substituted directly?
Usually not without evaluation. Solvency, boiling point, viscosity, reaction behavior, recovery and regulatory considerations can change process performance.
Which specification items matter beyond assay?
Common review items include water, acidity, color, residue and named impurities, but the final list should follow the application.
What should be confirmed before requesting a sample?
State the process, target grade, critical impurity limits, package preference, test method expectations and the quantity needed for qualification.
Reviewed by Xinchen Chemical Editorial Team. Procurement decisions should follow the agreed specification, current batch documents and destination requirements.